Idiopathic thrombocytopenic purpura: A 15‐year natural history study at the Children's Hospital Rijeka, Croatia

J Roganovic, M Letica‐Crepulja - Pediatric blood & cancer, 2006 - Wiley Online Library
Pediatric blood & cancer, 2006Wiley Online Library
We review a 15‐year experience with childhood idiopathic thrombocytopenic purpura (ITP)
at a tertiary‐care pediatric hospital in Croatia. Data confirm that ITP is typically a self‐limited
bleeding disorder that usually presents with mild symptoms in children between 1 and 10
years of age and affects both sexes equally. At presentation, more than half of the children
had platelet counts of< 10× 109/L. The absence of preceding viral infection and insidious
onset of symptoms were significantly associated with development of chronic ITP. In our …
Abstract
We review a 15‐year experience with childhood idiopathic thrombocytopenic purpura (ITP) at a tertiary‐care pediatric hospital in Croatia. Data confirm that ITP is typically a self‐limited bleeding disorder that usually presents with mild symptoms in children between 1 and 10 years of age and affects both sexes equally. At presentation, more than half of the children had platelet counts of <10 × 109/L. The absence of preceding viral infection and insidious onset of symptoms were significantly associated with development of chronic ITP. In our experience, observation without specific therapy seems to be the optimal approach to a child with ITP. Pediatr Blood Cancer 2006;47:662–664. © 2006 Wiley‐Liss, Inc.
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